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Viral Oncolysis That Targets Raf-1 Signaling Control of Nuclear Transport

The central role of Raf protein kinase isoforms in human cancer demands specific anti-Raf therapeutic inhibitors. Parvoviruses are currently used in experimental cancer therapy due to their natural oncotropism and lytic life cycle. In searching for mechanisms underlying parvovirus oncolysis, we foun...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Riolobos, Laura, Valle, Noelia, Hernando, Eva, Maroto, Beatriz, Kann, Michael, Almendral, José M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812376/
https://ncbi.nlm.nih.gov/pubmed/19939915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01550-09
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