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Insertion Mutations in Herpes Simplex Virus 1 Glycoprotein H Reduce Cell Surface Expression, Slow the Rate of Cell Fusion, or Abrogate Functions in Cell Fusion and Viral Entry

Of the four required herpes simplex virus (HSV) entry glycoproteins, the precise role of gH-gL in fusion remains the most elusive. The heterodimer gH-gL has been proposed to mediate hemifusion after the interaction of another required glycoprotein, gD, with a receptor. To identify functional domains...

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Autors principals: Jackson, Julia O., Lin, Erick, Spear, Patricia G., Longnecker, Richard
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812360/
https://ncbi.nlm.nih.gov/pubmed/20007280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02215-09
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