Multimerization of Hepatitis Delta Antigen Is a Critical Determinant of RNA Binding Specificity

Hepatitis delta virus (HDV) RNA forms an unbranched rod structure that is associated with hepatitis delta antigen (HDAg) in cells replicating HDV. Previous in vitro binding experiments using bacterially expressed HDAg showed that the formation of a minimal ribonucleoprotein complex requires an HDV u...

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Detalhes bibliográficos
Main Authors: Lin, Brian C., Defenbaugh, Dawn A., Casey, John L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Genome Replication and Regulation of Viral Gene Expression
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812348/
https://ncbi.nlm.nih.gov/pubmed/19923178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01723-09
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