Theiler's Murine Encephalomyelitis Virus L* Amino Acid Position 93 Is Important for Virus Persistence and Virus-Induced Demyelination

The DA strain and other members of the TO subgroup of Theiler's murine encephalomyelitis virus (TMEV) induce a persistent central nervous system infection associated with an inflammatory white matter demyelinating disease. TO subgroup strains synthesize an 18-kDa protein, L*, out of frame with...

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Hlavní autoři: Stavrou, Spyridon, Baida, Gleb, Viktorova, Ekaterina, Ghadge, Ghanashyam, Agol, Vadim I., Roos, Raymond P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2010
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812333/
https://ncbi.nlm.nih.gov/pubmed/19923182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01585-09
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