Critical Roles of Complement and Antibodies in Host Defense Mechanisms against Neisseria meningitidis as Revealed by Human Complement Genetic Deficiencies

Certain complement defects are associated with an increased propensity to contract Neisseria meningitidis infections. We performed detailed analyses of complement-mediated defense mechanisms against N. meningitidis 44/76 with whole blood and serum from two adult patients who were completely C2 or C5...

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Main Authors: Hellerud, Bernt Christian, Aase, Audun, Herstad, Tove Karin, Næss, Lisbeth Meyer, Kristiansen, Lisa Høyem, Trøseid, Anne-Marie Siebke, Harboe, Morten, Lappegård, Knut Tore, Brandtzæg, Petter, Høiby, E. Arne, Mollnes, Tom Eirik
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Bacterial Infections
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2812193/
https://ncbi.nlm.nih.gov/pubmed/19933829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01044-09
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