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An artificial glycoconjugate containing the bisphosphorylated glucosamine disaccharide backbone of lipid A binds lipid A monoclonal antibodies.

Monoclonal antibodies (MAbs) against lipid A, the endotoxic component of lipopolysaccharide (LPS) of gram-negative bacteria, are presently discussed as therapeutic agents against lethal gram-negative infections; however, their binding specificities are controversial. We have isolated from the LPS of...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Brade, L, Holst, O, Brade, H
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1993
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281192/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8406846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.10.4514-4517.1993
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