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Computational exploration of the network of sequence flow between protein structures
We investigate small sequence adjustments (of one or a few amino acids) that induce large conformational transitions between distinct and stable folds of proteins. Such transitions are intriguing from evolutionary and protein-design perspectives. They make it possible to search for ancient protein s...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2811751/ https://ncbi.nlm.nih.gov/pubmed/19899165 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.22622 |
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