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Regulatory T cells differentially modulate the maturation and apoptosis of human CD8+ T-cell subsets

The balanced manifestation of effector functions and the generation of long-living memory cells is a hallmark of efficient CD8+ T cell response. Accumulating data pinpoint regulatory CD4+ CD25(high) T cells (Treg) as a key factor for the inefficiency of CD8+ T cell responses in viral persistence. Li...

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Detalhes bibliográficos
Main Authors: Nikolova, Maria, Lelievre, Jean-Daniel, Carriere, Matthieu, Bensussan, Armand, Lévy, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811717/
https://ncbi.nlm.nih.gov/pubmed/19246340
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-04-151407
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