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Prostate cancer serum biomarker discovery through proteomic analysis of alpha-2 macroglobulin protein complexes

Alpha-2 macroglobulin (A2M) functions as a universal protease inhibitor in serum and is capable of binding various cytokines and growth factors. In this study, we investigated if immunoaffinity enrichment and proteomic analysis of A2M protein complexes from human serum could improve detection of bio...

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Detalhes bibliográficos
Main Authors: Burgess, Earle F., Ham, Amy-Joan L., Tabb, David L., Billheimer, Dean, Roth, Bruce J., Chang, Sam S., Cookson, Michael S., Hinton, Timothy J., Cheek, Kristin L., Hill, Salisha, Pietenpol, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811579/
https://ncbi.nlm.nih.gov/pubmed/20107526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prca.200780073
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