Optimizing oral vaccines: induction of systemic and mucosal B-cell and antibody responses to tetanus toxoid by use of cholera toxin as an adjuvant.

Cholera toxin (CT) is an effective mucosal antigen and acts as an adjuvant when given orally with various antigens; however, few studies have compared the levels of antibody responses to CT and coadministered protein in systemic and mucosal tissues. In this study, we used tetanus toxoid (TT) for ass...

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Veröffentlicht in:	Infect Immun
Hauptverfasser:	Jackson, R J, Fujihashi, K, Xu-Amano, J, Kiyono, H, Elson, C O, McGhee, J R
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Microbiology (ASM) 1993
Schlagworte:	Research Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281154/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8406816/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.10.4272-4279.1993
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