Use of transformation to construct antigenic hybrids of the class 1 outer membrane protein in Neisseria meningitidis.

The class 1 protein of Neisseria meningitidis is an important component of candidate outer membrane vaccines against meningococcal meningitis. This porin protein contains two variable regions which determine subtype specificity and provide binding sites for bactericidal monoclonal antibodies. To det...

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Autores principales: van der Ley, P, van der Biezen, J, Hohenstein, P, Peeters, C, Poolman, J T
Formato: Artigo
Lenguaje:Inglês
Publicado: 1993
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC281147/
https://ncbi.nlm.nih.gov/pubmed/7691745
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