Single Molecule Measurements of Interaction Free Energies Between the Proteins Within Binary and Ternary SNARE Complexes

We use an Atomic Force Microscope based single molecule measurements to evaluate the activation free energy in the interaction of SNARE proteins syntaxin 1A, SNAP25B and synaptobrevin 2 which regulate intracellular fusion of vesicles with target membranes. The dissociation rate of the binary syntaxi...

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Bibliographic Details
Main Authors: Liu, W., Montana, Vedrana, Parpura, Vladimir, Mohideen, U.
Format: Artigo
Language:Inglês
Published: 2009
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811379/
https://ncbi.nlm.nih.gov/pubmed/20107522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1166/jns.2009.1001
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