VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR SIGNALING IS REQUIRED FOR CARDIAC VALVE FORMATION IN ZEBRAFISH

Vascular endothelial growth factor-receptors (VEGF-Rs) are pivotal regulators of vascular development, but a specific role for these receptors in the formation of heart valves has not been identified. We took advantage of small molecule inhibitors of VEGF-R signaling and showed that blocking VEGF-R...

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Autors principals: Lee, You Mie, Cope, John J., Ackermann, Gabriele E., Goishi, Katsutoshi, Armstrong, Ehrin J., Paw, Barry H., Bischoff, Joyce
Format: Artigo
Idioma:Inglês
Publicat: 2006
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811314/
https://ncbi.nlm.nih.gov/pubmed/16170785
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dvdy.20559
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