Connexins regulate calcium signaling by controlling ATP release

Forced expression of gap junction proteins, connexins, enables gap junction-deficient cell lines to propagate intercellular calcium waves. Here, we show that ATP secretion from the poorly coupled cell lines, C6 glioma, HeLa, and U373 glioblastoma, is potentiated 5- to 15-fold by connexin expression....

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Detalhes bibliográficos
Main Authors: Cotrina, Maria Luisa, Lin, Jane H.-C., Alves-Rodrigues, Alexandra, Liu, Shujun, Li, Jiang, Azmi-Ghadimi, Hooman, Kang, Jian, Naus, Christian C. G., Nedergaard, Maiken
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 1998
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC28113/
https://ncbi.nlm.nih.gov/pubmed/9861039
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