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Reconstructing nonlinear dynamic models of gene regulation using stochastic sampling

BACKGROUND: The reconstruction of gene regulatory networks from time series gene expression data is one of the most difficult problems in systems biology. This is due to several reasons, among them the combinatorial explosion of possible network topologies, limited information content of the experim...

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Hlavní autoři: Mazur, Johanna, Ritter, Daniel, Reinelt, Gerhard, Kaderali, Lars
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811124/
https://ncbi.nlm.nih.gov/pubmed/20038296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-10-448
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