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PDGF-BB Mediates the Tropism of Human Mesenchymal Stem Cells for Malignant Gliomas

OBJECTIVE: Bone marrow-derived human mesenchymal stem cells (hMSCs) are capable of localizing to gliomas after systemic delivery and can be used in glioma therapy. However, the mechanism underlying the tropism of hMSCs for gliomas remains unclear. In vitro studies suggest that platelet derived growt...

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Autors principals: Hata, Nobuhiro, Shinojima, Naoki, Gumin, Joy, Yong, Raymund, Marini, Frank, Andreeff, Michael, Lang, Frederick F.
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2811094/
https://ncbi.nlm.nih.gov/pubmed/20023545
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1227/01.NEU.0000363149.58885.2E
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