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A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy

Many tumors, including lymphomas, up-regulate expression of CD46 to escape destruction by complement. Tumor cells are therefore relatively resistant to therapy by monoclonal antibodies, which act through complement-dependent cytotoxicity (CDC). From an Escherichia coli expression library of adenovir...

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Bibliografski detalji
Glavni autori: Wang, Hongjie, Liu, Ying, Li, Zong-Yi, Fan, Xiaolong, Hemminki, Akseli, Lieber, André
Format: Artigo
Jezik:Inglês
Izdano: American Society of Hematology 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810987/
https://ncbi.nlm.nih.gov/pubmed/19965652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-222463
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