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A recombinant adenovirus type 35 fiber knob protein sensitizes lymphoma cells to rituximab therapy
Many tumors, including lymphomas, up-regulate expression of CD46 to escape destruction by complement. Tumor cells are therefore relatively resistant to therapy by monoclonal antibodies, which act through complement-dependent cytotoxicity (CDC). From an Escherichia coli expression library of adenovir...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society of Hematology
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810987/ https://ncbi.nlm.nih.gov/pubmed/19965652 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-05-222463 |
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