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Amyloid β-peptide directly induces spontaneous calcium transients, delayed intercellular calcium waves and gliosis in rat cortical astrocytes

The contribution of astrocytes to the pathophysiology of AD (Alzheimer's disease) and the molecular and signalling mechanisms that potentially underlie them are still very poorly understood. However, there is mounting evidence that calcium dysregulation in astrocytes may be playing a key role....

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Hlavní autoři: Chow, Siu-Kei, Yu, Diana, MacDonald, Christopher L, Buibas, Marius, Silva, Gabriel A
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Neurochemistry 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810812/
https://ncbi.nlm.nih.gov/pubmed/20001968
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/AN20090035
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