Pharmacokinetics and pharmacodynamics of LC15-0444, a novel dipeptidyl peptidase IV inhibitor, after multiple dosing in healthy volunteers

AIMS: LC15-0444 is a selective and competitive inhibitor of dipeptidyl peptidase (DPP) IV with potential for the treatment of Type 2 diabetes. The aim was to investigate the pharmacokinetic (PK) and pharmacodynamic (PD) profiles after multiple oral ascending doses of LC15-0444 in healthy male subjec...

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Main Authors: Lim, Kyoung Soo, Cho, Joo-Youn, Kim, Bo-Hyung, Kim, Jung-Ryul, Kim, Hwa-Sook, Kim, Dong-Kyu, Kim, Sung-Ho, Yim, Hyeon Joo, Lee, Sung-Hack, Shin, Sang-Goo, Jang, In-Jin, Yu, Kyung-Sang
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2009
Assuntos:
Themed section: Obesity
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810799/
https://ncbi.nlm.nih.gov/pubmed/20002082
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2009.03376.x
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