BPDE-Induced Lymphocytic Chromosome 3p Deletions May Predict Renal Cell Carcinoma Risk

PURPOSE: Cigarette smoking is a risk factor for renal cell carcinoma (RCC). Benzo[α]pyrene diol expoxide (BPDE), a major constituent of cigarette smoke, induces 3p aberrations that are associated with susceptibility to other smoking-associated cancers. Because chromosome 3p deletions are known to th...

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Bibliographic Details
Main Authors: Zhu, Yimin, Horikawa, Yohei, Yang, Hushan, Wood, Christopher G., Habuchi, Tomonori, Wu, Xifeng
Format: Artigo
Language:Inglês
Published: 2008
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810745/
https://ncbi.nlm.nih.gov/pubmed/18433782
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.juro.2008.01.092
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