Anthracycline Cardiomyopathy Is Mediated by Depletion of the Cardiac Stem Cell Pool and Is Rescued by Restoration of Progenitor Cell Function

BACKGROUND: Anthracyclines are the most effective drugs available in the treatment of neoplastic diseases. However, they have profound consequences on the structure and function of the heart causing with time a cardiomyopathy that leads to congestive heart failure. METHODS AND RESULTS: Administratio...

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Main Authors: De Angelis, Antonella, Piegari, Elena, Cappetta, Donato, Marino, Laura, Filippelli, Amelia, Berrino, Liberato, Ferreira-Martins, João, Zheng, Hanqiao, Hosoda, Toru, Rota, Marcello, Urbanek, Konrad, Kajstura, Jan, Leri, Annarosa, Rossi, Francesco, Anversa, Piero
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810713/
https://ncbi.nlm.nih.gov/pubmed/20038740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.109.895771
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