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Monitoring the Erosion of Hydrolytically-Degradable Nanogels via Multiangle Light Scattering Coupled to Asymmetrical Flow Field-Flow Fractionation

We describe the synthesis and characterization of degradable nanogels that display bulk erosion under physiologic conditions (pH = 7.4, 37 °C). Erodible poly(N-isopropylmethacrylamide) nanogels were synthesized by copolymerization with N,O-(dimethacryloyl)hydroxylamine, a cross-linker previously use...

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Detalhes bibliográficos
Main Authors: Smith, Michael H., South, Antoinette B., Gaulding, Jeffrey C., Lyon, L. Andrew
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810709/
https://ncbi.nlm.nih.gov/pubmed/20000662
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac901725m
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