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Proteomic Parsimony through Bipartite Graph Analysis Improves Accuracy and Transparency

Assembling peptides identified from LC–MS/MS spectra into a list of proteins is a critical step in analyzing shotgun proteomics data. As one peptide sequence can be mapped to multiple proteins in a database, naïve protein assembly can substantially overstate the number of proteins found in samples....

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Detalhes bibliográficos
Main Authors: Zhang, Bing, Chambers, Matthew C., Tabb, David L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810678/
https://ncbi.nlm.nih.gov/pubmed/17676885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/pr070230d
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