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Effect of cAMP on TGFβ1-Induced Corneal Keratocyte–Myofibroblast Transformation

PURPOSE: TGFβ is the major mediator to induce myofibroblast differentiation in the corneal wound-healing process. Elevated cAMP can reduce TGFβ-induced fibrosis in other tissues. This study was conducted to determine whether elevated cAMP can inhibit TGFβ1-induced rabbit corneal keratocyte–myofibrob...

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Hlavní autoři: Xing, Dongmei, Bonanno, Joseph A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810623/
https://ncbi.nlm.nih.gov/pubmed/18936144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2444
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