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Selective Toxin Sequestrants for the Treatment of Bacterial Infections
Bacterial toxin-mediated diarrheal disease is a major cause of morbidity and mortality worldwide. In this work we designed an on-bead library of protease-resistant, acid-stable peptoid molecules and screened for high affinity binding of cholera toxin. From 100,000 compounds, we discovered a single s...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810561/ https://ncbi.nlm.nih.gov/pubmed/19351156 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja900852k |
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