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A synthetic analog of the 3-deoxy-D-manno-2-octulosonic acid disaccharide moiety of rough-type endotoxins does not bind to mouse peritoneal macrophages and human monocytes.

Strong evidence supports the concept that lipid A is the main biologically active region of endotoxins and is recognized by specific binding sites of different cell types. However, receptors for carbohydrates are also present on mononuclear phagocytes, and it has been suggested that one of these lec...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Girard, R, Pedron, T, Kosma, P, Chaby, R
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281056/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7689537/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.9.3616-3624.1993
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