CyaC-mediated activation is important not only for toxic but also for protective activities of Bordetella pertussis adenylate cyclase-hemolysin.

Bordetella pertussis adenylate cyclase-hemolysin (AC-Hly), encoded by the cyaA gene, belongs to the RTX family of toxins with extensive glycine-rich repeats in the carboxy-terminal portion. AC-Hly possesses both adenylate cyclase toxic and hemolytic activities that depend on a posttranslational modi...

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Detalhes bibliográficos

Publicado no:	Infect Immun
Principais autores:	Betsou, F, Sebo, P, Guiso, N
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1993
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC281051/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8359880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.9.3583-3589.1993
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