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Total Synthesis of the Antimitotic Bicyclic Peptide Celogentin C

An account of the total synthesis of celogentin C is presented. A right-to-left synthetic approach to this bicyclic octapeptide was unsuccessful due to an inability to elaborate derivatives of the right-hand ring. In the course of these efforts, it was discovered that the mild Braslau modification o...

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Detalhes bibliográficos
Main Authors: Ma, Bing, Banerjee, Biplab, Litvinov, Dmitry N., He, Liwen, Castle, Steven L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810426/
https://ncbi.nlm.nih.gov/pubmed/20038144
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja909870g
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