Architecture of the RNA polymerase II–TFIIF complex revealed by cross-linking and mass spectrometry

Higher-order multi-protein complexes such as RNA polymerase II (Pol II) complexes with transcription initiation factors are often not amenable to X-ray structure determination. Here, we show that protein cross-linking coupled to mass spectrometry (MS) has now sufficiently advanced as a tool to exten...

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Autors principals: Chen, Zhuo Angel, Jawhari, Anass, Fischer, Lutz, Buchen, Claudia, Tahir, Salman, Kamenski, Tomislav, Rasmussen, Morten, Lariviere, Laurent, Bukowski-Wills, Jimi-Carlo, Nilges, Michael, Cramer, Patrick, Rappsilber, Juri
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810376/
https://ncbi.nlm.nih.gov/pubmed/20094031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.401
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