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WASP plays a novel role in regulating platelet responses dependent on αIIbβ3 integrin outside-in signaling
The most consistent feature of Wiskott-Aldrich syndrome (WAS) is profound thrombocytopenia with small platelets. The responsible gene encodes WASP (WAS protein), which functions in leukocytes as an actin filament nucleating agent – yet – actin filament nucleation proceeds normally in patient platele...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810352/ https://ncbi.nlm.nih.gov/pubmed/19863535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2141.2009.07959.x |
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