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Evolution of Highly Polymorphic T Cell Populations in Siblings with the Wiskott-Aldrich Syndrome
Population level evolutionary processes can occur within a single organism when the germ line contains a mutation that confers a cost at the level of the cell. Here we describe how multiple compensatory mutations arose through a within-individual evolutionary process in two brothers with the immune...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2567846/ https://ncbi.nlm.nih.gov/pubmed/18941616 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003444 |
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