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Orbitofrontal inactivation impairs reversal of Pavlovian learning by interfering with disinhibition of responding for previously unrewarded cues

Orbitofrontal cortex (OFC) is critical for reversal learning. Reversal deficits are typically demonstrated in complex settings that combine Pavlovian and instrumental learning. Yet recent work has implicated the OFC specifically in behaviors guided by cues and the features of the specific outcomes t...

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Detalhes bibliográficos
Main Authors: Burke, Kathryn A, Takahashi, Yuji K., Correll, Jessica, Brown, P Leon, Schoenbaum, Geoffrey
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810348/
https://ncbi.nlm.nih.gov/pubmed/19912335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1460-9568.2009.06992.x
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