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TROSY-selected ZZ-exchange experiment for characterizing slow chemical exchange in large proteins

A TROSY-selected ZZ-exchange experiment is described for measuring slow chemical exchange rates by monitoring the TROSY component of (15)N longitudinal magnetization. Application of the proposed pulse sequence to the cadherin 8 N-terminal extracelluar domain demonstrates that enhanced sensitivity is...

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Detalhes bibliográficos
Main Authors: Li, Ying, Palmer, Arthur G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810196/
https://ncbi.nlm.nih.gov/pubmed/19890725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10858-009-9385-0
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