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Mitochondrial dysfunction in mouse models of Parkinson's disease revealed by transcriptomics and proteomics

It has been long thought that neuronal loss in Parkinson's disease (PD) is related to reactive oxygen species from mitochondrial dysfunction. However, there have been few investigations surveying both transcriptome and proteome in PD. This review focuses on recent work using microarrays and mas...

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Autor principal: Smith, Desmond J.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810189/
https://ncbi.nlm.nih.gov/pubmed/19967437
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10863-009-9254-2
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