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Induction of B7-H1 and B7-DC expression on airway epithelial cells by the Toll-like receptor 3 agonist double-stranded RNA and human rhinovirus infection: In vivo and in vitro studies

BACKGROUND: T-cell infiltration of the epithelium is a key feature of chronic rhinosinusitis and asthma. Viral infections are an important cause of disease exacerbations. We have found virus-induced expression of T cell–interacting ligands, B7 homolog costimulatory molecules, on airway epithelium. O...

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Detalhes bibliográficos
Main Authors: Heinecke, Lowella, Proud, David, Sanders, Scherer, Schleimer, Robert P., Kim, Jean
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810151/
https://ncbi.nlm.nih.gov/pubmed/18378285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaci.2008.02.009
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