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Outsmarting a Mastermind
Moellering et al. recently reported that a cell-permeable “stapled” synthetic peptide of the Notch coactivator Mastermind is a potent dominant-negative inhibitor of oncogenic Notch signaling in T cell acute lymphoblastic leukemia. This new class of inhibitor may find broad utility in blocking protei...
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| Hovedforfatter: | |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810139/ https://ncbi.nlm.nih.gov/pubmed/20059945 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.12.002 |
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