Centrosomal Nlp is an oncogenic protein that is gene-amplified in human tumors and causes spontaneous tumorigenesis in transgenic mice

Disruption of mitotic events contributes greatly to genomic instability and results in mutator phenotypes. Indeed, abnormalities of mitotic components are closely associated with malignant transformation and tumorigenesis. Here we show that ninein-like protein (Nlp), a recently identified BRCA1-asso...

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Detalhes bibliográficos
Main Authors: Shao, Shujuan, Liu, Rong, Wang, Yang, Song, Yongmei, Zuo, Lihui, Xue, Liyan, Lu, Ning, Hou, Ning, Wang, Mingrong, Yang, Xiao, Zhan, Qimin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810077/
https://ncbi.nlm.nih.gov/pubmed/20093778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI39447
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