TGF-β activity protects against inflammatory aortic aneurysm progression and complications in angiotensin II–infused mice

Complicated abdominal aortic aneurysm (AAA) is a major cause of mortality in elderly men. Ang II–dependent TGF-β activity promotes aortic aneurysm progression in experimental Marfan syndrome. However, the role of TGF-β in experimental models of AAA has not been comprehensively assessed. Here, we sho...

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Main Authors: Wang, Yu, Ait-Oufella, Hafid, Herbin, Olivier, Bonnin, Philippe, Ramkhelawon, Bhama, Taleb, Soraya, Huang, Jin, Offenstadt, Georges, Combadière, Christophe, Rénia, Laurent, Johnson, Jason L., Tharaux, Pierre-Louis, Tedgui, Alain, Mallat, Ziad
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810071/
https://ncbi.nlm.nih.gov/pubmed/20101093
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI38136
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