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Neural Wiskott-Aldrich syndrome protein modulates Wnt signaling and is required for hair follicle cycling in mice

The Rho family GTPases Cdc42 and Rac1 are critical regulators of the actin cytoskeleton and are essential for skin and hair function. Wiskott-Aldrich syndrome family proteins act downstream of these GTPases, controlling actin assembly and cytoskeletal reorganization, but their role in epithelial cel...

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Bibliografiske detaljer
Main Authors: Lyubimova, Anna, Garber, John J., Upadhyay, Geeta, Sharov, Andrey, Anastasoaie, Florentina, Yajnik, Vijay, Cotsarelis, George, Dotto, Gian Paolo, Botchkarev, Vladimir, Snapper, Scott B.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2810069/
https://ncbi.nlm.nih.gov/pubmed/20071778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI36478
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