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Preparation and Characterization of Rodent Intestinal Microsomes: Comparative Assessment of Two Methods
Small intestine plays an important role in the first-pass metabolism of orally ingested xenobiotics as a result of expression of both Phase I and Phase II metabolic enzymes, together with associated transporters. Intestinal microsomes thus can be used to study susceptibility of compounds to metaboli...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Medknow Publications
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2810057/ https://ncbi.nlm.nih.gov/pubmed/20177465 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4103/0250-474X.51968 |
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