Ventromedial Hypothalamic Nitric Oxide Production Is Necessary for Hypoglycemia Detection and Counterregulation

OBJECTIVE: The response of ventromedial hypothalamic (VMH) glucose-inhibited neurons to decreased glucose is impaired under conditions where the counterregulatory response (CRR) to hypoglycemia is impaired (e.g., recurrent hypoglycemia). This suggests a role for glucose-inhibited neurons in the CRR....

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Autori principali: Fioramonti, Xavier, Marsollier, Nicolas, Song, Zhentao, Fakira, Kurt A., Patel, Reema M., Brown, Stacey, Duparc, Thibaut, Pica-Mendez, Arnaldo, Sanders, Nicole M., Knauf, Claude, Valet, Philippe, McCrimmon, Rory J., Beuve, Annie, Magnan, Christophe, Routh, Vanessa H.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Diabetes Association 2010
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Original Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809968/
https://ncbi.nlm.nih.gov/pubmed/19934009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db09-0421
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