TRIM5α Modulates Immunodeficiency Virus Control in Rhesus Monkeys

The cytoplasmic TRIM5α proteins of certain mammalian lineages efficiently recognize the incoming capsids of particular retroviruses and potently restrict infection in a species-specific manner. Successful retroviruses have evolved capsids that are less efficiently recognized by the TRIM5α proteins o...

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Bibliographic Details
Main Authors: Lim, So-Yon, Rogers, Thomas, Chan, Tiffany, Whitney, James B., Kim, Jonghwa, Sodroski, Joseph, Letvin, Norman L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809762/
https://ncbi.nlm.nih.gov/pubmed/20107597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000738
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