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A Novel 3-D Mineralized Tumor Model to Study Breast Cancer Bone Metastasis

BACKGROUND: Metastatic bone disease is a frequent cause of morbidity in patients with advanced breast cancer, but the role of the bone mineral hydroxyapatite (HA) in this process remains unclear. We have developed a novel mineralized 3-D tumor model and have employed this culture system to systemati...

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Detalhes bibliográficos
Main Authors: Pathi, Siddharth P., Kowalczewski, Christine, Tadipatri, Ramya, Fischbach, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809751/
https://ncbi.nlm.nih.gov/pubmed/20107512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008849
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