Contribution of Proteus mirabilis urease to persistence, urolithiasis, and acute pyelonephritis in a mouse model of ascending urinary tract infection.

Proteus mirabilis, a significant cause of bacteriuria and acute pyelonephritis in humans, produces urease. This high-molecular-weight, multimeric, cytoplasmic enzyme hydrolyzes urea to ammonia and carbon dioxide. To assess the role of urease in colonization, urolithiasis, and acute pyelonephritis in...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Johnson, D E, Russell, R G, Lockatell, C V, Zulty, J C, Warren, J W, Mobley, H L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC280917/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8514376/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.61.7.2748-2754.1993
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