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Reduced expression of glutamate receptors and phosphorylation of CREB are responsible for in vivo Δ9-THC exposure-impaired hippocampal synaptic plasticity

Chronic use of marijuana impairs synaptic plasticity and cognitive function. However, the molecular mechanisms by which marijuana alters long-term synaptic plasticity are largely unknown. Here we show that repeated in vivo exposures to Δ9-THC for 7 consecutive days significantly impaired hippocampal...

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Main Authors: Fan, Ni, Yang, Hongwei, Zhang, Jian, Chen, Chu
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809144/
https://ncbi.nlm.nih.gov/pubmed/19912468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06489.x
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