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Amongst eligible patients, age and comorbidity do not predict for dose limiting toxicity from phase I chemotherapy

BACKGROUND: There are no clear predictors clinicians can use to determine who is more likely to experience dose limiting toxicity (DLT) in phase I chemotherapy clinical trials. Many providers are reluctant to refer older adults to phase I trials because of concerns about the development of toxicity....

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Autori principali: LoConte, Noelle K., Smith, Maureen, Alberti, Dona, Bozeman, Jeffrey, Cleary, James F., Setala, Ashley N., Wodtke, Geoff, Wilding, George, Holen, Kyle D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809128/
https://ncbi.nlm.nih.gov/pubmed/19649630
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-009-1084-8
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