Systemic Administration of Antiretrovirals Prior to Exposure Prevents Rectal and Intravenous HIV-1 Transmission in Humanized BLT Mice

Successful antiretroviral pre-exposure prophylaxis (PrEP) for mucosal and intravenous HIV-1 transmission could reduce new infections among targeted high-risk populations including discordant couples, injection drug users, high-risk women and men who have sex with men. Targeted antiretroviral PrEP co...

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Main Authors: Denton, Paul W., Krisko, John F., Powell, Daniel A., Mathias, Melissa, Kwak, Youn Tae, Martinez-Torres, Francisco, Zou, Wei, Payne, Deborah A., Estes, Jacob D., Garcia, J. Victor
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809117/
https://ncbi.nlm.nih.gov/pubmed/20098623
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0008829
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