Gene expression relationship between prostate cancer cells of Gleason 3, 4 and normal epithelial cells as revealed by cell type-specific transcriptomes

BACKGROUND: Prostate cancer cells in primary tumors have been typed CD10(-)/CD13(-)/CD24(hi)/CD26(+)/CD38(lo)/CD44(-)/CD104(-). This CD phenotype suggests a lineage relationship between cancer cells and luminal cells. The Gleason grade of tumors is a descriptive of tumor glandular differentiation. H...

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Autors principals: Pascal, Laura E, Vêncio, Ricardo ZN, Page, Laura S, Liebeskind, Emily S, Shadle, Christina P, Troisch, Pamela, Marzolf, Bruz, True, Lawrence D, Hood, Leroy E, Liu, Alvin Y
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2009
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2809079/
https://ncbi.nlm.nih.gov/pubmed/20021671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-9-452
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