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Measuring cis-acting regulatory variants genome-wide: new insights into expression genetics and disease susceptibility
Regulatory polymorphisms have emerged as a prevalent source of phenotypic variability, capable of driving rapid evolution. mRNA profiling combined with genome-wide genotyping of polymorphisms has revealed pervasive genetic influences on gene expression, acting both in cis and in trans. Measuring all...
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
BioMed Central
2009
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2808732/ https://ncbi.nlm.nih.gov/pubmed/20090894 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm116 |
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